Have you ever wondered why that pill you’re taking for pain isn’t really helping, or why it’s causing side effects? Well, the “one size fits all” strategy for medicines is yielding to genetic profiling that predicts disease risk and drug response in a way that personalizes medicine. Mary Dugan-Jordan, an oncology nurse has suffered from pain for 12 years and tried many medicines without much relief. Pharmacogenetic testing made a noticeable difference in her pain, and her ability to function. Dr. Anita Gupta, pain specialist and pharmacist from Drexel University College of Medicine helps us understand the value of pharmacogentic testing and its application for patients and healthcare providers.